, a developer of innovative medicines for serious central nervous system illnesses, announced today that it offers acquired access to medical data helping a zinc-structured therapy for the prevention of infections in the elderly. This acquisition expands and enhances Adeona’s zinc-based item candidate portfolio that already contains its proprietary zinc-structured tablets for use in the dietary management of mild to moderate Alzheimer’s disease and moderate cognitive impairment sufferers, and age-related macular degeneration. In addition, Adeona also announced the appointment of the zinc analysis pioneer, Ananda S. Prasad, M.D., Ph.D., to the Company’s Scientific Advisory Panel. ‘I am pleased to sign up for the Scientific Advisory Plank of Adeona, a ongoing company leading the advancement of zinc-centered therapies addressing illnesses in the elderly,’ stated Ananda S.In multivariate logistic versions, a PA:A ratio of more than 1 was the element that had the strongest association with severe exacerbations at both time points . Separate multivariate zero-inflated binomial regression versions confirmed that a PA:A ratio greater than 1 was connected with an increased frequency of severe exacerbations at 12 months . Association between PA:A Ratio and All Exacerbations In multivariate regression analyses of data from the COPDGene longitudinal follow-up cohort, the presence of an increased PA:A ratio was also associated with a rise in the occurrence of any exacerbation , as well as in the frequency of the events . In the ECLIPSE validation cohort, a PA:A ratio greater than 1 was connected with all exacerbations at 1 year and at three years . Multivariate zero-inflated binomial regression models confirmed that a PA:A ratio of more than 1 was individually associated with an increase in the rate of recurrence of all exacerbations at 12 months in the ECLIPSE cohort .