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Efficacy Outcomes The ultimate number of primary efficacy events was 572, or 61.0 percent of the initially planned number. In the intention-to-treat analysis, the principal efficacy final result of cardiovascular death, myocardial infarction, or ischemic stroke occurred in 279 sufferers assigned to apixaban and in 293 sufferers assigned to placebo . Comparable results were seen in an on-treatment evaluation . There were also no significant differences between your apixaban and placebo groupings with respect to the secondary efficacy outcomes . The result of apixaban as compared with placebo was similar among patients receiving combination antiplatelet therapy and among those receiving aspirin alone. The rates of the primary efficacy outcome among individuals who were receiving mixture antiplatelet therapy were 7.2 percent in the apixaban group and 7.5 percent in the placebo group , and the corresponding rates among those receiving aspirin alone were 9.0 percent and 9.8 percent .