For each component of the principal final result and for secondary scientific outcome occasions such as myocardial infarction, unstable angina, and stroke, similar strategies were utilised without correction for multiple screening. All of the reported subgroup analyses were prespecified before the database was locked and so are shown in the statistical analysis plan . Outcomes Characteristics of the Sufferers, Procedural Characteristics, and Hospital Course From 2011 through February 2014 April, a complete of 970 patients were enrolled at 42 hospitals in three countries, with 475 patients assigned to the cyclosporine group and 495 to the control group. The intention-to-treat analysis included each one of these patients aside from 1 in the cyclosporine group who did not provide written educated consent.These metrics consist of functions such as for example swallow rate, pharyngeal transit time – enough time it takes liquid to become swallowed through the pharynx , or throat, and into the esophagus, or food tube – and the real number of ineffective swallows through the esophagus. The researchers discovered that healthy ageing mice develop symptoms of swallowing impairment that closely resemble the impairments seen in older adults: generally slowed swallowing function, impaired tongue function, larger size of the total amount swallowed and a rise in the period it takes liquid to travel through the throat to the tummy. We're going to change the landscape of dysphagia intervention, Lever said.